Human growth secretion is highest around puberty and continues to decline thereafter. The volume of growth hormone falls around 14% between age 21 and 31 for every ten years, whereas daily hormone creation rate is reduced by 50% by the time you are 60 years old. As you age, the decline in the rate of secretion causes decreased serum levels of Insulin-like Growth Factor-1 (IGF-1) as well as reduced release of hormone from the hypothalamus. The best way to learn about your growth hormone levels is by measuring plasa IGF-1 levels – anything less than 350 IU is known to be a proof of deficiency.
The core cause of age-related decline in GH secretion, though, is not known, experts claim it results from increased secretion of GH-inhibiting hormone, also known as Somatostatin. Some researchers are of the view that because Sematostatin increases with age, it prevents the release of Growth Hormone and blocks actions that enhance further growth. Secondly, some experts believe that decrease in GH is due to another major Growth Hormone Releasing Hormone (GHRH), known as Precursor Hormone, which becomes less responsive when it comes to feedback signals as you age. Chances are that both of these things might be happening at the same times, hence leading to rapid GH deficiencies. HGH for sale shop.
Causes of Decline in HGH Levels with Age
Aging is usually accompanied by physiological effects such as a decrease in lean mass and lower bone density. Associated with these anti-aging effects is Somatopause which involves frailty, relative obesity, increased frequency of fractures and major sleep disorders. Doctors call this physiologic decline in growth hormones as we age, “Sematopause”. There could be numerous reasons that might contribute to this such as:
– A decline in amino acid precursor required by the pituitary gland for the regular production of HGH.
– Lack of certain nutrients in your diet may also lead to decrease in production of GHRH as is the case in diabetes where high blood sugar levels reduce the hormone releasing activity.
– Growing older also leads to increased stress and trauma, which result in hypothalamus losing its ability to produce or discharge GHRH (Growth Hormone releasing Hormone).
– With age, factors such as stress, emotional trauma, illnesses due to lack of nutrition, infections and various other actions in hormonal glands could also lead to a decline in master hormone in the body, which carries the most comprehensive effect on your wellness as you age.
– The core hormone that releases growth hormone, known as GHRH, tends to become less responsive with age and may cause a significant decline in HGH.
– Somatostatin, which inhibits production of growth hormones, increases with age and eventually blocks the actions that help improve HGH in the body.
– Similarly, hypothalamus might sustain the release of stimulatory hormones that produce growth hormones, while somatostatin, the hormone that inhibits its production, might increase.
– Normally, when IGF-1 fails to perform, it immediately sends a message to the hypothalamus to stimulate the pituitary so it can produce additional growth hormones. However, as you age, the feedback loop begins to malfunction and eventually breaks down.
Aging is a complex process which brings about many hormonal ups and downs in the body. Research demonstrates benefits of low-dose GH therapy in individuals after running some necessary tests on them.
Stay young! Stay healthy!